Summary:
- Researchers have discovered that metformin, a widely prescribed diabetes medication, significantly alters the gut microbiome to improve blood glucose regulation.
- The drug promotes the growth of specific bacteria that absorb excess glucose from the bloodstream into the intestinal wall, effectively turning the gut into a "sink" for sugar.
- This study provides a mechanistic explanation for how metformin's interaction with the microbiome contributes to its therapeutic efficacy beyond its traditional pathways in the liver.