Equitable research partnerships recognise and aim to mitigate against the power imbalances that exist within the global research ecosystem. What are the approaches to research that bolster research in the Global South and seek to reverse inequities within the research ecosystem? There were several recommendations made at the roundtable discussion which we hope will add to the broader conversations about equitable research partnerships. The Roundtable, which took place at BMA House in December 2022, was supported by WHO’s Special Programme TDR and the ESSENCE on Health Research initiative