PASTE, Don’t Cut: Genome Editing Tool Looks Beyond CRISPR and Prime

TL;DR

A recently patented genome editing tool called PASTE holds genuine promise for expanding the universe of treatable genetic diseases. PASTE“We have compared, side-by-side, fused and unfused prime editors plus integrases at several different target sites in human cells, and we have never observed any benefit from fusing the prime editor and integrase,” said Liu, who is also the director of the Merkin Institute of Transformative Technologies in Healthcare and a Howard Hughes Medical Institute investigator. 0 situation, where who are we going to take a license to turns on, who do we think is going to win the patent fight, taking a license for prime [editing] or PASTE turns on what is our actual technology, which to be blunt is how we want the licensing system to work,” Sherkow said

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