- PMID: 33341328- PMCID: PMC7695568- DOI: 10.1016/j.mehy.2020.110395AbstractWe present the hypothesis to the scientific community actively designing clinical trials and recommending public health guidelines to control the pandemic that - "Tetanus vaccination may be contributing to reduced severity of the COVID-19 infection" - and urge further research to validate or invalidate the effectiveness of the tetanus toxoid vaccine against COVID-19.This hypothesis was revealed by an explainable artificial intelligence system unleashed on open public biomedical datasets.As a foundation for scientific rigor, we describe the data and the artificial intelligence system, document the provenance and methodology used to derive the hypothesis and also gather potentially relevant data/evidence from recent studies.Nature.2020;11 - PMC - PubMed-- Gysi DM, Valle ID, Zitnik M, Ameli A, Gan X, Varol O, Sanchez H, Baron R, Ghiassian D, Loscalzo J, Barabasi A-L. Network medicine framework for identifying drug repurposing opportunities for covid-19."