A new drug seeks 'true revenge' on COVID by turning the virus against itself

TL;DR

A new drug seeks 'true revenge' on COVID by turning the virus against itselfA neurologist at a prestigious U.S. research institute has developed an experimental COVID treatment he calls “true revenge” that weaponizes the virus against itself.Now a COVID antiviral, NMT5—if approved by the U.S. Food and Drug Administration—would be taken orally by an infected person much like Paxlovid, the popular pills taken at home by those who’ve been diagnosed with the virus.But unlike Paxlovid, which prevents COVID from replicating in an infected person’s body, NMT5 alters the virus, causing it to gain “warheads” that temporarily alter the cells where COVID usually attaches and enters so that the virus is no longer capable of infecting them.Those infected with COVID who take the new drug are expected to spread virus that destroys itself—meaning it should be unable to infect a new host, according to the study.Yet another bonus: In addition to being taken in pill form, the drug can also be inhaled, meaning it can immediately diffuse to the lungs and nasal passages, where the virus enters the body, ideally preventing further spread."

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